How do you even notice a mouse cable?
It is literally opposite of where your hand is!
I still use an old mouse, I got from someone who works in IT.
You can comfortably rest your hand on it and the buttons can effortlesly clicked, though they are started fail recently and it has a scrollwheel.
I once got a (wireless) gaming mouse, but I found it to be extremly uncomfortable, to constantly grasp its shape.
I used it with a netbook a couple of times after that, until it mysteriously broke.