The real subsumption of labor is an important element of class conflict to analyze. The design of the means of production is an important way in which the bourgeoisie maintain power. But I am unsure of how the working class may fight the professional strata who design the means of production.
It seems to me that the professional strata only profits from a share of temporary super-profits due to innovation. If the workers want to fuck with the scientists then they must fight the intellectual monopoly rents the techs make their money from. It seems to me that rather than smashing mills the Luddites should have leaked the mill designs and trade secrets to their employer's competitors.