A Soviet drug better than caffeine!
THE WORKING MAN'S COFFEE!
Bromantane (trade name Ladasten / Ладастен) is a Russian pharmaceutical substance developed in the late 1980s that possesses both stimulant and anxiolytic properties.[2] Although it is a commonly used medication in Russia and surrounding countries, it has not gained widespread recognition or pharmaceutical use in other countries. During the 1996 Olympic Games in Atlanta, 5 different Russian athletes tested positive for bromantane use.[3]
A study conducted on human subjects displayed bromantane's ability to improve endurance and work capacity during stressful and intense conditions.[4] This is because bromantane works as an actoprotector, a substance that makes the body more stable under physical duress without increasing oxygen consumption.[5]
Bromantane is a chemical derivative of adamantane, a polyhedral organic compound containing four fused cyclohexane rings. Bromantane's structure consists of adamantane bound at R2 to a nitrogenous group which is in turn bonded to a phenyl ring substituted at R4 with a bromine group.
Bromantane is atypical among stimulants in the sense that it inhibits serotonin reuptake in addition to inhibiting dopamine reuptake. It also increases levels of norepinephrine, but its means of doing so are unclear.[6] Bromantane's anxiolytic properties are due to its strengthening of GABA-ergic mediation.[5]
Unlike typical stimulants such as amphetamine, bromantane's effects come primarily through the upregulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase (L-DOPA decarboxylase).[7] Rodent studies have shown a 2-2.5x increase in these enzymes following administration of bromantane, and their upregulation causes a downstream increase in levels of dopamine, serotonin and epinephrine.
Although not relevant at clinical dosages, bromantane has been found to produce anticholinergic effects, including both antimuscarinic and antinicotinic actions, at very high doses in animals.[8][9]
Subjective effects
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
Physical effects
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Stimulation - It is generally not described as forced and is mild comparing to that produced by typical stimulants like amphetamine.
Stamina enhancement
Dehydration[citation needed]
Vasoconstriction[citation needed]
Increased blood pressure[citation needed]
Muscle relaxation[citation needed]
Tactile enhancement - Bromantane can cause warm pleasurable skin feeling simillar to that produced by empathogens like MDMA but the effect is far less pronounced.[citation needed]
Teeth grinding - Although bromantane has muscle relaxing properties it can cause jaw clenching especially when mixed with caffeine.[citation needed]
Cognitive effects
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Anxiety suppression - Bromantane produces anxiety supression which is unusual comparing to typical stimulants like amphetamine which can actually cause feelings of anxiety.
Focus enhancement
Thought acceleration
Analysis enhancement
Memory enhancement
Motivation enhancement
Cognitive euphoria
Wakefulness
Increased music appreciation - It appears less consistently and the effect is less pronounced comparing to typical stimulants like amphetamine.
phenibut lowkey one of my favorite downers will have to look into this OP